Human Gene GABRA3 (uc010ntk.1) Description and Page Index
Description: Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), mRNA. RefSeq Summary (NM_000808): GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.180828.1, SRR1660803.154983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370314.9/ ENSP00000359337.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## Transcript (Including UTRs) Position: hg19 chrX:151,335,634-151,619,831 Size: 284,198 Total Exon Count: 10 Strand: - Coding Region Position: hg19 chrX:151,336,700-151,533,042 Size: 196,343 Coding Exon Count: 9
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Comments and Description Text from UniProtKB
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Genetic Association Studies of Complex Diseases and Disorders
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MalaCards Disease Associations
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Comparative Toxicogenomics Database (CTD)
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Common Gene Haplotype Alleles
Generated from 1000 Genomes Phase1 variants (help). Note the association of SNP alleles within a haplotype is statistically imputed rather than directly observed in most cases.
Restricted to 0 non-synonymous, common variant sites with a frequency of occurrence of at least 1%.
0 non-reference haplotypes were found using common variants.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
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Protein Domain and Structure Information
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Orthologous Genes in Other Species
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Descriptions from all associated GenBank mRNAs
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Biochemical and Signaling Pathways
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Other Names for This Gene
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Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_000808.3
exon count:
10
CDS single in 3' UTR:
no
RNA size:
2785
ORF size:
1479
CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
3158.00
frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0
# strange splices:
0
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Methods, Credits, and Use Restrictions
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