ERalpha_a |
Rabbit polyclonal affinity purified antibody. Epitope is the C-terminus of human estrogen receptor alpha (ESR1). Antibody Target: ESR1 |
ESR1 |
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5-prime UTRs and use different promoters. (provided by RefSeq) |
Santa Cruz Biotechnology sc-543 |
Ruan, Myers |
Human - ERalpha a(Immunoprecipitation-Western blot,IP-MassSpec)
|
C2510 G1509 |
GeneCard:ESR1 |
ERalpha a (sc-543) |