CCNT2 |
Goat polyclonal. Raised against an internal region of human CycT2a/b. Antibody Target: CCNT2 |
CCNT2 |
CycT2 is one of three cyclins that can form a heterodimer with cyclin-dependent kinase 9 (CDK9). The heterodimer is known as positive elongation factor b (P-TEFb) and is responsible for the phosphophorylation of Ser2 of the heptad repeat in the C-terminal domain of RNA polymerase II as well as the negative elongation factors DSIF (hSpt4/hSpt5) and NELF. Phosphorylation of RNA polymerase II and the negative elongation factors by P-TEFb promotes elongation. CycT2 contains a leucine rich domain capable of binding to the C-terminal domain of RNA polymerase II. |
Santa Cruz Biotechnology sc-12419 |
Struhl |
Human - missing
|
H2306 |
GeneCard:CCNT2 |
CCNT2 (sc-12419) |