Description
This track shows the SNPs that were used in the calculation of Tajima's D
(Tajima, 1989), a measure of nucleotide
diversity, estimated from the Perlegen data set (Hinds et al., 2005).
Tajima's D is a statistic used to compare an observed nucleotide
diversity against the expected diversity under the assumption that all
polymorphisms are selectively neutral and constant population size.
The original SNP coordinates were from the Human May 2004 assembly;
they were transformed to this assembly using UCSC's liftOver program.
Methods
See the Tajima's D track or Carlson et al. for more details on the
use of this track.
Credits
This track was created at the University of Washington using gfetch
from the Nickerson Laboratory and the R statistical software package.
References
Tajima F.
Statistical method for testing the neutral mutation hypothesis
by DNA polymorphism.
Genetics 1989 Nov;123(3):585-95.
Carlson CS, Thomas DJ, Eberle M, Livingston R, Rieder M, Nickerson DA.
Genomic regions exhibiting positive selection identified from
dense genotype data.
Genome Res 2005 Nov;15(11):1553-65.
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