Description
The miRNA track shows microRNAs from
miRBase.
Display Conventions and Configuration
The precursor forms of
microRNAs (mirs) in the sense
orientation are shown in black; those in the reverse orientation are colored
grey.
To display only those items that exceed a specific unnormalized score, enter
a minimum score between 0 and 1000 in the text box at the top of the track
description page. For this track, a score of 960 signifies that the miRNA is on the + strand and a
score of 480 signifies that it is on the - strand.
Methods
Precursor miRNA genomic locations from
miRBase
were calculated using wublastn for sequence alignment with the requirement of
100% identity. The extents of the precursor sequences were not generally known,
and were predicted based on base-paired hairpin structure. miRBase is
described in Griffiths-Jones, S. et al. (2006). The miRNA Registry
is described in Griffiths-Jones, S. (2004) and Weber, M.J. (2005) in the
References section below.
Credits
Genome coordinates for this track were obtained from the miRBase sequences
FTP site.
References
When making use of these data, please cite the folowing articles in addition to
the primary sources of the miRNA sequences:
Griffiths-Jones S, Saini HK, van Dongen S, Enright AJ.
miRBase: tools for microRNA genomics.
Nucleic Acids Res. 2008 Jan 1;36(Database issue):D154-8.
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ.
miRBase: microRNA sequences, targets and gene nomenclature.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.
Griffiths-Jones S.
The microRNA Registry.
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D109-11.
Weber MJ.
New human and mouse microRNA genes found by homology search.
Febs J. 2005 Jan;272(1):59-73.
The following publication provides guidelines on miRNA annotation:
Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X,
Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M et al.
A uniform system for microRNA annotation.
RNA. 2003 Mar;9(3):277-9.
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